RTG 2737 – STRESSistance

Publications

2025

  • Probst A, Knochenhauer D, Niemeyer J, Fischer L, Schroda M (2025) Internalization of affinity tags enables the purification of secreted Chlamydomonas proteins. Curr Genet 71, 7. https://doi.org/10.1007/s00294-025-01311-2

  • Amponsah PS, Bökenkamp JE, Kurpa O, Lenhard S, Myronova A, Vega Velazquez DO, Hirschelmann C, Behrends C, Herrmann JM , Räschle M, Storchová Z (2025) Aneuploidy-induced proteostasis disruption impairs mitochondrial functions and mediates aggregation of mitochondrial precursor proteins through SQSTM1/p62. Nat Commun, accepted. Preprint: https://www.biorxiv.org/content/10.1101/2024.07.29.605607v1 (bioRxiv)

  • Ebding J, Mazzone F, Kins S, Pielage J, Maritzen T (2025) How neurons cope with oxidative stress. Biol Chem 2025 Feb 25. doi: 10.1515/hsz-2024-0146. Epub ahead of print. PMID: 39988910. https://doi.org/10.1515/hsz-2024-0146

  • Bökenkamp JE, Keuper K, Redel S, Barthel K, Johnson L, Becker A, Wieland A, Räschle M, Storchová Z (2025) Proteogenomic analysis reveals adaptive strategies for alleviating the consequences of aneuploidy in cancer. EMBO J. https://doi.org/10.1038/s44318-025-00372-w

2024

  • Tamanna SS, Boden JS, Kaiser KM, Wannicke N, Hoering J, Sanchez-Baracaldo P, Deponte M, Frankenberg-Dinkel N, & Gehringer MM (2024). Early-branching cyanobacteria up-regulate superoxide dismutase activity under a simulated early Earth anoxic atmosphere. Geobiology 22, e70005. https://doi.org/10.1111/gbi.70005

 

  • Jung F, Rödl S, Herrmann JM, Mühlhaus T (2024) Analysis and prediction of internal mitochondrial targeting signals. Methods Enzymol 2024;706, 263-283. https://doi.org/10.1016/bs.mie.2024.07.038 (book chapter)

 

  • Cheng J*, Arystanbek Kyzy M*, Heide A, Khan A, Lehmann M, Schröder L, Nägele T, Pommerrenig B, Keller I, Neuhaus HE (2024) SAST1 is a tonoplast located protein and impacts TOR and SnRK1.1 activities for controlled senescence. Plant Physiol 19, kiae430. https://doi.org/10.1093/plphys/kiae430. *shared first authorship.

 

 

  • Bertgen L, Bökenkamp J-E, Schneckmann T, Koch C, Räschle M, Storchová Z, Herrmann JM (2024) Distinct types of intramitochondrial protein aggregates protect mitochondria against proteotoxic stress. Cell Rep 43, 1-23. https://doi.org/10.1016/j.celrep.2024.114018

 

  • Katrin Hieronimus, Tabea Donauer, Jonas Klein, Bastian Hinkel, Julia Vanessa Spänle, Anna Probst, Justus Niemeyer, Salina Kibrom, Anna Maria Kiefer, Luzia Schneider, Britta Husemann, Eileen Bischoff, Sophie Möhring, Nicolas Bayer, Dorothée Klein, Adrian Engels, Benjamin Gustav Ziehmer, Julian Stieß, Pavlo Moroka, Michael Schroda, and Marcel Deponte (2024) A Modular Cloning Toolkit for the production of recombinant proteins in Leishmania tarentolae. Microbial Cell 11, 128- 142; doi: 10.15698/mic2024.04.821 https://microbialcell.com/researcharticles/2024a-hieronimus-microbial-cell/

 

 

  • Geissel F*, Lang L*, Husemann B, Morgan B, and Deponte M (2024) Deciphering the mechanism of glutaredoxin-catalyzed roGFP2 redox sensing reveals a ternary complex with glutathione for protein disulfide reduction. Nature Commun 15,1733, https://doi.org/10.1038/s41467-024-45808-9

 

  • Bohle F, Rossi J, Tamanna S, Jansohn H, Schlosser M, Reinhardt F, Brox A, Bethmann S, Kopriva S, Trentmann O, Jahns P, Deponte M, Schwarzlander M, Trost P, Zaffagnini M, Meyer AJ, Müller-Schüssele SJ (2024) Chloroplasts lacking class I glutaredoxins are functional but show a delayed recovery of protein cysteinyl redox state after oxidative challenge. Redox Biol 69, 103015, https://doi.org/10.1016/j.redox.2023.103015

2023

  • Lenhard S, Gerlich S, Khan A, Rödl S, Bökenkamp JE, Peker E, Zarges C, Faust J, Storchova Z, Räschle M, Riemer J, Herrmann JM (2023) The Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis. J Cell Biol 222: e202303002, https://doi.org/10.1083/jcb.202303002

 

  • Vollweiter D, Shergill JK, Hilse A, Kochlamazashvili G, Koch SP, Muelle S, Boehm-Sturm P, Haucke V, Maritzen T (2023) Intersectin deficiency impairs cortico-striatal neurotransmission and causes obsessive–compulsive behaviors in mice. PNAS 120, e2304323120, https://doi.org/10.1073/pnas.2304323120

 

  • Bischoff E, Lang L, Zimmermann J, Luczak M, Kiefer AM, Niedner-Schatteburg G, Manolikakes G, Morgan B, Deponte M (2023) Glutathione kinetically outcompetes reactions between dimedone and a cyclic sulfenamide or physiological sulfenic acids. Free Radic Biol Med 208,165-177, https://www.sciencedirect.com/science/article/pii/S0891584923005774

 

  • Siitonen V, Probst A, Tóth G, Kourist R, Schroda M, Kosourov S, Allahverdiyeva Y (2023). Engineered green alga Chlamydomonas reinhardtii as a whole-cell photosynthetic biocatalyst for stepwise photoproduction of H2 and ε-caprolactone. Green Chemistry 25, 5945-5955. https://doi.org/10.1039/D3GC01400B

 

 

 

  • Jung F, Frey K, Zimmer D, Mühlhaus T (2023) DeepSTABp: A deep learning approach for the prediction of thermal protein stability. Int J Mol Sci 24, 7444. https://doi.org/10.3390/ijms24087444

 

  • Simakin P, Koch C, Herrmann J (2023) A modular cloning (MoClo) toolkit for reliable intracellular protein targeting in the yeast Saccharomyces cerevisiae. Microbial Cell 10, 78 – 87. DOI: 10.15698/mic2023.04.794

 

2022

 

  • Rödl S, den Brave F, Räschle M, Kizmaz B, Lenhard S, Groh C, Becker H, Zimmermann J, Morgan B, Becker T, Herrmann MJ (2022) The metabolite-controlled ubiquitin conjugase Ubc8 promotes mitochondrial protein import. Life Sci Alliance 6, e202201526. DOI: 10.26508/lsa.202201526

 

  • Mushtaq Z, Aavula K, Lasser DA, Kieweg ID, Lion LM, Kins S, Pielage J (2022) Madm/NRBP1 mediates synaptic maintenance and neurodegeneration-induced presynaptic homeostatic potentiation. Cell Reports 41, 111710. https://doi.org/10.1016/j.celrep.2022.111710

 

  • Kiefer AM, Niemeyer J, Probst A, Erkel G, Schroda M (2022) Production and secretion of functional SARS-CoV-2 spike protein in Chlamydomonas reinhardtii. Front Plant Sci 13, 988870. https://doi.org/10.3389/fpls.2022.988870 

 

  • Bernhard SV, Seget-Trzensiok K, Kuffer C, Krastev DB, Stautmeister LM, Theis M, Keuper K, Boekenkamp JE, Kschischo M, Buchholz F, Storchova Z (2022) Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling. Cell Oncol (Dordr) 45, 103-119. https://doi.org/10.1007/s13402-021-00654-5